The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
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منابع مشابه
Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis.
Two pathways are initiated upon 3T3-L1 preadipocyte differentiation: the reentry of cells into the cell cycle and the initiation of a cascade of transcriptional events that "prime" the cell for differentiation. The "priming" event involves the synthesis of members of the CCAAT/enhancer binding protein (C/EBP) family of transcription factors. However, the relationship between these two pathways ...
متن کاملRb regulates C/EBP -DNA-binding activity during 3T3-L1 adipogenesis
Cole, Kathryn A., Anne W. Harmon, Joyce B. Harp, and Yashomati M. Patel. Rb regulates C/EBP -DNA-binding activity during 3T3-L1 adipogenesis. Am J Physiol Cell Physiol 286: C349–C354, 2004. First published October 22, 2003; 10.1152/ajpcell.00255.2003.—Two pathways are initiated upon 3T3-L1 preadipocyte differentiation: the reentry of cells into the cell cycle and the initiation of a cascade of ...
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The 3T3-L1 cell line is a well-established and commonly used in vitro model to assess adipocyte differentiation. Over the course of several days, confluent 3T3-L1 cells can be converted to adipocytes in the presence of an adipogenic cocktail. In this study, the effects of chitosan oligosaccharides (CO) on adipocyte differentiation of 3T3-L1 cells were studied. The CO significantly decreased lip...
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Flavonoids, polyphenolic compounds that exist widely in plants, inhibit cell proliferation and increase cell differentiation in many cancerous and noncancerous cell lines. Because terminal differentiation of preadipocytes to adipocytes depends on proliferation of both pre- and postconfluent preadipocytes, we predicted that flavonoids would inhibit adipogenesis in the 3T3-L1 preadipocyte cell li...
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Adipose tissue development and function play a critical role in the regulation of energy balance, lipid metabolism, and the pathophysiology of metabolic syndromes. Although the effect of zinc ascorbate supplementation in diabetes or glycemic control is known in humans, the underlying mechanism is not well described. Here, we investigated the effect of a zinc-chelated vitamin C (ZnC) compound on...
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ژورنال
عنوان ژورنال: Adipocyte
سال: 2020
ISSN: 2162-3945,2162-397X
DOI: 10.1080/21623945.2020.1795422